A rare neuroblastoma location in the pelvis

  • Stanko Cavar
  • Marko Bogovic
  • Dino Papes
  • Suzana Srsen-Medancic
  • Hrvoje Jednacak
  • Tatjana Zah-Bogovic
  • Anko Antabak
  • Ivana Sabolic-Pipinic
  • Miram Pasini
  • Tomislav Luetic
Keywords: neuroblastoma, pelvic tumor

Abstract

Neuroblastoma is the most common extracranial solid malignant tumor in children that is most often located inthe abdomen (suprarenal gland, sympathetic chain) and mediastinum, while other locations are rare. The treatment is surgery, chemotherapy and radiotherapy. In this article we present a rare case of neuroblastoma originating from sacral plexus in a 9-month-old female infant, with infiltration of the obturator channel. We performed tumor extirpation with paraaortal and iliacal lymphadenectomy, while a small portion of the tumor remained in the obturator channel because the attempt of complete removal would carry a significant risk of nerve damage. Radical removal is not recommended because it carries a high risk of nerve damage without improving overall survival.

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References

Hoehner JC, Gestblom C, Hedborg F, et al. A developmental model of neuroblastoma: differentiating stroma-poor tumors' progress along an extra-adrenal chromaffin lineage. Lab Invest 1996;75: 659−675.

Maris JM. Recent advances in neuroblastoma. N Engl J Med 2010;362: 2202−2211.

Maris JM, Hogarty MD, Bagatell R, et al. Neuroblastoma. Lancet 2007;369: 2106−2120.

DeVita, Hellman, Rosenberg (eds). Cancer: Principles and Practice of Oncology. 7th ed. Philadelphia: Wolters Kluwer, Lippincott Williams & Wilkins; 2005.

London WB, Castleberry RP, Matthay KK, et al. Evidence for an age cutoff greater than 365 days for neuroblastoma risk group stratification in the Children's Onclogy Group. J Clin Oncol 2005;23: 6459−6465.

Cohn SL, Pearson AD, London WB, et al. INRG Task Force. The International Neuroblastoma Risk Group (INRG) classification system: an INRG Task Force report. J Clin Oncol 2009;27: 289−297.

Shimada H, Ambros IM, Dehner LP, et al. The International Neuroblastoma Pathology Classification (the Shimada system). Cancer 1999;86: 364−372.

Brodeur GM, Pritchard J, Berthold F, et al. Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment. J Clin Oncol 1993;11: 1466−1477.

Friedman GK, Castleberry RP. Changing trends of research and treatment in infant neuroblastoma. Pediatr Blood Cancer 2007;49: 1060–1065.

Leclair MD, Hartmann O, Heloury Y, et al. Localized pelvic neuroblastoma: excellent survival and low morbidity with tailored therapy − the 10-year experience of the French Society of Pediatric Oncology. J Clin Oncol 2004;22: 1689−1695.

Cruccetti A, Kiely EM, Spitz L, et al. Pelvic neuroblastoma: low mortality and high morbidity. J Pediatr Surg 2000;35(5): 724−728.

Shuster J, Matthay KK, Haas-Kogan D, et al. Neuroblastoma. In: Halperin EC, Constine LS, Tarball NJ, Kun LE (eds) Pediatric radiation oncology. 4th ed. Philadelphia: Lippincott Williams & Wilkins; 2005.

Published
2013-08-20
How to Cite
1.
Cavar S, Bogovic M, Papes D, Srsen-Medancic S, Jednacak H, Zah-Bogovic T, Antabak A, Sabolic-Pipinic I, Pasini M, Luetic T. A rare neuroblastoma location in the pelvis. Acta Chir. Croat. [Internet]. 2013Aug.20 [cited 2020Oct.28];10(1):29-1. Available from: https://acc.hkd.com.hr/index.php/ACC/article/view/27
Section
Case Reports