ALPPS - new approach in the treatment of advanced liver tumors

  • Bosko Romic University Hospital Centre Zagreb
  • Ivan Romic University Hospital Centre Zagreb
  • Mate Skegro University Hospital Centre Zagreb
  • Tomislav Baotic University Hospital Centre Zagreb
  • Igor Petrovic University Hospital Centre Zagreb
  • Ognjan Deban University Hospital Centre Zagreb
  • Goran Pavlek University Hospital Centre Zagreb
  • Jurica Zedelj University Hospital Centre Zagreb
Keywords: ALPPS, liver resection, hypertrophy


ALPPS (Associated Liver Partition and Portal Vein Ligation for Staged Hepatectomy) is an innovative surgical procedure which was presented for the first time in 2012, and in last two years it has become widely accepted by hepatobiliary surgeons and cosequently three ALPPS procedures have been performed at our institution so far. Considering that ALPPS is a relatively new method, indicated only in carefully selected patients, we still expect studies on larger number of patients, but according to last results ALPPS has proved to be a very successful surgical method which allows resectability of tumors that were considered irresectable, by promoting surprisingly fast and intensive hypertrophy of future liver remnant.


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How to Cite
Romic B, Romic I, Skegro M, Baotic T, Petrovic I, Deban O, Pavlek G, Zedelj J. ALPPS - new approach in the treatment of advanced liver tumors. Acta Chir. Croat. [Internet]. 2016Dec.15 [cited 2021Dec.7];13(1):15-0. Available from: