Congenital hyperinsulinism - surgical treatment and complications

  • Marko Bogovic
  • Stipe Batinica
  • Tomislav Luetic
  • Anko Antabak
  • Stanko Cavar
  • Suzana Srsen-Medancic
Keywords: hyperinsulinism, hypoglycaemia, pancreatectomy, partial pancreatectomy, choledochal obstruction, choledochal lesion


Congenital hyperinsulinism is a common cause of persistent hypoglycaemia in neonates. Cases resistant to medicamentous therapy require surgical treatment, where the greatest challenge is to differentiate focal from diffuse forms of the disease and to localize the focal lesion. PET-scan, selective arterial stimulation and venous sampling (ASVS) and intraoperative frozen sections examination are used to determine the type. Partial pancreatectomy for focal forms has lower complication rate and diabetes mellitus development than radical neartotal pancreatectomy for diffuse forms. We report a case of a 6-month-old boy with focal form of CHI with special emphasis on surgical complications of pancreas resection together with their management.


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How to Cite
Bogovic M, Batinica S, Luetic T, Antabak A, Cavar S, Srsen-Medancic S. Congenital hyperinsulinism - surgical treatment and complications. Acta Chir. Croat. [Internet]. 2011Dec.1 [cited 2024Feb.21];8(1):21-5. Available from:
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